Email: [email protected]

cryoDRGN Github: https://github.com/ml-struct-bio/cryodrgn

Getting started

You will need access to python via Anaconda to run create an environment and install cryoDRGN. You may be able to access an cryoDRGN or Anaconda as a module if you are working on a managed cluster.

Running Anaconda from a module is okay but regardless of whether you’re working from a managed cluster or a standalone workstation we recommend installing cryoDRGN locally to ensure you have the latest release.

If you do not have access to Anaconda we recommend installing miniconda.

CryoDRGN_QuickStart-1.pdf

More documentation and tutorials are available in the official cryoDRGN user guide

Create and activate conda environment

(base) $ conda create --name cryodrgn python=3.13
(cryodrgn) $ conda activate cryodrgn

Install cryoDRGN

(cryodrgn) $ pip install cryodrgn

Optional - View cryodrgn and cryodrgn_utils documentation

cryodrgn --help
cryodrgn_utils --help

Navigate to the cryoDRGN project directory that has been created for you and check that you have a data directory and initial results directory

cd cryodrgn/00_cryodrgn_tutorial
ls

SPA Walkthrough: EMPIAR-10874